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Internet Electronic Journal of Molecular Design - IEJMD, ISSN 1538-6414, CODEN IEJMAT
| ABSTRACT - Internet Electron. J. Mol. Des. September 2007, Volume 6, Number 9, 271-279 |
Monty Kier and the Origin of the Pharmacophore Concept
John H. Van Drie
Internet Electron. J. Mol. Des. 2007, 6, 271-279
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Abstract:
The historical evolution of the concept of a pharmacophore is presented,
from its initial articulation by Kier in the late 1960's to its current
implementations in commonly-used modeling software. Its impact on a
variety of different areas of computer-aided drug design is described.
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