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Internet Electronic Journal of Molecular Design - IEJMD, ISSN 1538-6414, CODEN IEJMAT
ABSTRACT - Internet Electron. J. Mol. Des. December 2002, Volume 1, Number 12, 668-674

Numerical Characterization of DNA Primary Sequence
Ping-an He and Jun Wang
Internet Electron. J. Mol. Des. 2002, 1, 668-674

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Abstract:
In a previous paper, the authors defined a numerical characterization of DNA primary sequences. A DNA primary sequence was reduced to a few of binary sequences, based on the classifications of the four nucleic acid bases. The reduced sequences are called the characteristic sequences. For each characteristic sequence, we associated two 2x2 matrices, the elements of which are given by the frequency of occurrence of all (0,1) triplets in the characteristic sequence. In this paper, we use eigenvalues of the new matrices to characterize the biological functions of purine-pyrimidine, amino-keto groups and weak-strong H-bonds, respectively.

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